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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc256c95bee733883d62f09dd8acc31efb404e76c7c731e938b3e12de203bc2' 
  AND token = 'km4aeYfEzm0lB044IFm9LVpvLRdopEDk54Z98mw+PkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}