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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e41dfbabbaae68714b107358b4bd29fe9bf62d417923a2961e32c635575210f2' 
  AND token = 'qYJ/W3f7hplfjaTNLgEbMAONiDp2OhS7Gfx+f7vTa5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}