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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e54569f86c599e98a8404f8ea586a0ffeac38d6892a4b04dd1d94cebc65a2d' 
  AND token = 'y+sFKMjUq608K+urGXnfgI0EH/tl4A9tzyBU4dHnkcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}