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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a4ef7b0e3961f74bb677cc14f9200b410e73a926e5482b88c843e00ffbc506' 
  AND token = 'Mchoz9OGTZy91Aodb4Lchq7uDJ20BgAaP0evxWndU3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}