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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135c46072a33c46544e7fefcea9df6152bbefdb53a10e61ad467ac551a6aa4b6' 
  AND token = 'Jb4j1M1nzqBc/k3YY2nBzvLJ2jGpSCiCi8YcZGV/Y/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}