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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cd3d59045c6670406f5287ae15eaa534fabe8d9d3ead12d1f0a9abf94c3a7c' 
  AND token = 'UmHbRJKkBfKM62l9gas1p/EkYPw41koiDtz5LXrysKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}