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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6808d83ec33b6a7787dc33fdbcd197759b9eed30c40573a6c4e05a6c01920c29' 
  AND token = 'YvH1VHfKTPROXHsIbonAGrFUsi3/LVdp8IHxaAhC9wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}