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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa745f1425de7ca8a4a2b956646a48746c0d2c1825b41eca6caad1c7e64be846' 
  AND token = 'ZkkOl1EHLNzW+7bc/qaEuLt9E2s1MfXPONPhQd/g3hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}