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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9f9b7f2c995844096fda76ce2733aa685a22aaa72f0523151b8198b29573c21' 
  AND token = 'cwo0ZdI8cipKQ95VgaxhTNshl2WtUlcloyoaHFU3pLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}