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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60185c57e5ab4738dfe9810f4357e726adf877e634f08480dd0b194c9bfaae7' 
  AND token = 'wQ/nt9k+Qh6cxLMJMoNAEq6zPwPbR2Hv4TV+x56FEaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}