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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95f24937870377abc04d749e8edde9f5d0b0b36de6ba0d0133a0410aa86d25a8' 
  AND token = 'K35oLQbrH9ub2ioto9v7P8RYuLSeES8Jz0PtZpvCwPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}