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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d36a56f1992f25ca31cf28096911853f2173354d3862a2ec834d1ef4559b6ee' 
  AND token = 'rwQVVMqLSHclYhIANbQWTmq0FFbRi43nl/EqQ5IYLEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}