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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389078891ee2d0e6b760e3d5e09d201dc6ab3d7005a689227b1bb34503e1a556' 
  AND token = 'y8yOwM14jBBkdIMBD9Ui5sOMnpKmt5PEWQfNTqZHy9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}