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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8789a148dc4529985b77e1969e04808f71bc28043ffb79a636b4baa058a1711e' 
  AND token = '5rpIl8PcvpY1RTEdMthpsxORVISwWCWeL+yWUuKXkqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}