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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459cf67838331982ede88d348b4c8b6c007491da639dd6f1972020100c319d01' 
  AND token = '/EGpYmVqtLizJrnx5LusfQLH09LZlFqcr5y2SBGqsuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}