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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f04bd421014b27d5bb9382a1a73d6c9922af7645dfb6053b84f4ea4673ccb244' 
  AND token = 'qSbCJTx8CTAK1VGYDv0+erHDTgVIIJ3/QiWs6Kb1yEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}