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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e19236a041c3f507e284d8bdd4a4cb77b08bf06ad6fc7fdc187b76f536e611' 
  AND token = 'qSCFZcvVYoyXkS5ho+c0/MW8tLF5bvvUh3oz3tPml3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}