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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322a8f6a31a18cbfa9b051e7aae5e2fdf844a46e4747e50bc9d17473aec0ad30' 
  AND token = 'AD0O9DuDPH0eDFrgZO+1GLUczHoV5Yp41lQZ65pKkXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}