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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c41eb0f5b8808f1d9798981f158d9ebf273233731253198176bc5d29fa8d1f5' 
  AND token = 't5sETFjDGRk3oZG8bDGjIFEc1lJITDB5a0Q7CNRbznk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}