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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8844db161f0d3fc32188598f04068443b3fc7e6de48ae6fa21fa9bcdfb8bc8df' 
  AND token = 'F/pHXmIo9Rx+4F23weosAkNKf3dq4qwI0iD4ESz9vMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}