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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c427ca8d7dba42b76ab6794374a0667cf493ae5349739129dd54db1d1f59b078' 
  AND token = 'HMUd3tS32+CpRpROpXNep5BUGTxfuFv0WTXe/sWS2Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}