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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4ef32183a8c718ba1a730258e078d8541c9cc3d0ee329be950446c15521a37' 
  AND token = 'akq9KWorc0YQgKWMKZFBBj8rXLPQrNv87trFOeW6KQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}