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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a7a4c12bc2a5f28ffea1703af085a7cd4c8bba4f3d31353ed9cf8df18dc07a' 
  AND token = '8uLZSiihhukLieG8+a2eHQZ7SGoqgoxEZqlixmPsYxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}