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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3b234d991ca2a46f2ec4548f0231594b70e7bc5988b11791c3f5291f41f429' 
  AND token = 'sVt+diT2lDR8I3As3c5MfJttt+UowXDPATf9EIvo8eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}