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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b3f0e320d08c2f887099f92147c2b0f894f9c7136bc76036b3c34802645ad5' 
  AND token = 'BL/oD970VCBgkeiYKTWnYEcfl48/SYP/0RpphZEMdfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}