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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7edf21b4cea29d0e384ed436fc9e887fd4cecb77c7fd98a40549761a74a42e' 
  AND token = 'giiWgU2We+ImnvqQ1F7P2anz97n9Ir8XRZKl+fJ3DOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}