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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d5bb12a4743c18c3760f9888435cb174c4bb59ab8d285afd9d860f69059ddc' 
  AND token = 'IGKP6ix8yA11u62bU5V1lAk58iGr/2oar2PFr6hv3PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}