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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f533eec873f99cee9d38c11cf28c35e36b58bff528c5c2308c29963ed013b21d' 
  AND token = '54QDSXEV0Op7at/X0vB+aTGBvYq0LDj0t1WB9mf0Bsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}