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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301394a29014f024e2fb4fc045de9413321ab63323a2170b5d6dafd305d3f48a' 
  AND token = 'QDHOzacMM4W75NTQwZz52MJxaNGtV1IpzL2t9DF1FbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}