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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18aa0a041b30c7caba1034abbb46358023cf809f9252c2ddb4b8e7974a3d044' 
  AND token = 'UOyn6lympF10Fw4isHDAYMzbjUFdy1w+kFAPmQAzqUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}