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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4370205f59fcd6f593ff729f5e6cee5b0f3ea3a472a5b42cf430ca08a6eff209' 
  AND token = '8USDXANjRfoJlM7SO6LM+6ck4Q2yLPlwcIZuA9iH/KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}