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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146fede51c1aec2601bdc24662b0bd2e075318e3440a112593299f29ade10904' 
  AND token = 'syKVUCiCJ4UOyyGikVXj+0TurDoxLPvUw4wg51OgoS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}