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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9999277559bff601d618adbcd619a21623a8b53ccdd34a312f51bc4598e8af94' 
  AND token = 'eZAqdrgaRaNLQGoFTprQM9Ixq1M9MCqXZdJiD2eGvSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}