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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed63152a6f57a581a4afd5379dc73bc2ceee6cfd2681d0c217ac8aa5f271e1b' 
  AND token = '95M7ppIePRU2ylxPfrUfU1V2BRVmnWRaNg9GeWUTzi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}