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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef0bf87c3700c7c1c9c37560395d65f5be4ddef0621138027967abcc7d824fb' 
  AND token = 'GCD4bEeUtE221X516vsSBgS+WtLjDtrDmwwhE2DFlJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}