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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da3661379fa9857f6f96ce59154a5c52b2b5925964c07bea87534b9ee2f7776' 
  AND token = 'irLS1XvdIEUFd4pwuwodhbTVn4Ca1ZurZ4wEJ2OQnRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}