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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d80dc813c910d54218caa49be79c83f7f2953b7f3d5891f081a57ef2543e0ae' 
  AND token = 'f1Kgh2uE9gTvUwgIN21TAcT9xiJNKdT8gPEgLmDLVf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}