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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c499f3b6cba1ac2c596f14cb81c6114815a015f2084f75017c4efcab23db523' 
  AND token = 'VQRkrP0rfGezBb7FPbZcZ3y1/7odjh3VUq2J3FsmQPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}