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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3775c2261c31d7880382d171e18982db519943e4b5ad2a7bb5976b936a4ddf98' 
  AND token = 'hjt3SxwMsvRzjFlZr75V1Qpc3Z8CNO6ED2Xbug6kbgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}