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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf265a229a823697657d11291bd77272a663adc51aa835ac069b4619f11f0ff' 
  AND token = 'l8QeUj5y2MQSsS/Xs9vxaxDUN0lLwj2UUQ/9KgAMgqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}