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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45af9df67466e31bbe27ef109891a8e3e7032126927f90d2fee511d9b1e627a2' 
  AND token = 'ikElGumCmROcrTyCr0Qjcq+AcS8y8gfM7BI0tbYMVdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}