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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc633f86d3e2d184f50c2efe9cdd64786b0466ada33075c6a5c3ecb41a41c4ca' 
  AND token = 'In7UocJuIfjEXiU+cw9XizloimkR5rK/hw4UU4Il9ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}