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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec13a8ebf76ccaa3236b48ee2281f71579b3f79b313a414c7a4e4cd946c4c131' 
  AND token = '4JTgjyybMYV8kwn1RhcXLh8EUzqo5p4X7+O0v5TuBDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}