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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cfd655ed3767058826bf26b335508af611178754c87ec3e559a35c104e70a7f' 
  AND token = '4PEb35AZvIxbCEKrVvIDShrSAsKHMVZL3qglpmoY47M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}