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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43303ff773935b66d35b7dc28efc6f996c55d9063340c8c01988092d9061d247' 
  AND token = 'HJpnTXB3RU6Z0YodRPm2HqhizqlT1A64SPXg/Dxm3aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}