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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a333983a82f197826a36b589b2ea7dfcc7433202decd7ade8675e712caa00da9' 
  AND token = 'e4J3F++P53RJGC2Jmi6l8PHIHFxDyoX2G3FLzR7j6Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}