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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ce8ef5165a5534f16bb452f78f16952f8415401c1d8a55f76902203daac5b9' 
  AND token = '9k/aRzj8IH/dsS6OmRYySXezghqwM85CQ0m35xLy9eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}