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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c1bea386904eee238f04006a6272fde25acf18700e0c527e99056074705011' 
  AND token = '01VzsFBADgrvA3afMa4sWNeyz+Z1+s2taj+XxBe6pC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}