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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c048b039d0cf4df8352a36dea7c1ff7f4e8626bba1452bd858ea542794090c' 
  AND token = '+uN6yBIeHFLRvqiD1YL2KrQFLnqH5ye8bqN4VpL1wps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}