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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31c9ab09037f41bcf7fdddaaf98f44cbfb59e8378b221d511bfc37cdb8c98ca1' 
  AND token = 'VACKY+1KFEMzdDh2zcf2MyO5fSI29EZxWWNpFA2hde4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}